ADR Ontology |
ADR Term |
Osteoporosis |
ADR ID |
BADD_A03222 |
ADR Hierarchy |
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Description |
A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. [CTCAE] Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. [MeSH] |
MedDRA Code |
10031282 |
MeSH ID |
D010024
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Synonym |
Bone fragile | Disuse osteoporosis | Idiopathic osteoporosis | Osteoporosis | Osteoporosis NOS | Osteoporosis steroid-induced | Osteoporosis, unspecified | Other osteoporosis | Osteoporomalacia | Osteoporoses | Osteoporosis, Post-Traumatic | Osteoporosis, Post Traumatic | Post-Traumatic Osteoporoses | Post-Traumatic Osteoporosis | Osteoporosis, Senile | Osteoporoses, Senile | Senile Osteoporoses | Osteoporosis, Involutional | Senile Osteoporosis | Osteoporosis, Age-Related | Osteoporosis, Age Related | Bone Loss, Age-Related | Age-Related Bone Loss | Age-Related Bone Losses | Bone Loss, Age Related | Bone Losses, Age-Related | Age-Related Osteoporosis | Age Related Osteoporosis | Age-Related Osteoporoses | Osteoporoses, Age-Related |
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ADR Related Proteins |
Protein Name |
UniProt AC |
TTD Target ID |
Adenylate kinase isoenzyme 1 | P00568 | Not Available | Parathyroid hormone/parathyroid hormone-related peptide receptor | Q03431 | T67710 |
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Drugs Leading to the ADR |
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